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identifier: 1418705
description:
epitope description:SPDVDLGDISGINAS
antigen name:Spike glycoprotein
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 17392374
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1005028
landingPage: http://www.iedb.org/assay/1418705
type:
Literature
publicationVenue:
J Virol
dates:
2007
study type: b cell assays
subject species: SARS coronavirus
fullName:
Jincun Zhao
Qianrong Huang
Wei Wang
Yan Zhang
Ping Lv
Xiao-Ming Gao
method:
biological activity
name:
Identification and characterization of dominant helper T-cell epitopes in the nucleocapsid protein of severe acute respiratory syndrome coronavirus.
description:
Significant inhibition of SARS pseudovirus (where SARS spike protein is expressed in HIV-luciferase pseudotyped virus) infectivity of Vero cells is seen only in sera from mice immunized with fusion peptides that contain a T helper epitope derived from SARS nucleoprotein. In mice immunized with this peptide alone or with a mixture of this peptide and the T helper peptides, no response is seen. .

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