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identifier: 1419706
description:
epitope description:ASQPGSSEPSNPVSSGHSVSTVSVSQTSTSSEKQDTIQ
antigen name:Other Plasmodium falciparum (malaria parasite P. falciparum) protein
host organism:Mus musculus BALB/c
antibody name:Mouse sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 17875342
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1005969
landingPage: http://www.iedb.org/assay/1419706
type:
Literature
publicationVenue:
Peptides
dates:
2007
study type: b cell assays
subject species: Plasmodium falciparum UF-5
fullName:
Shinji L Okitsu
Francesca Boato
Markus S Mueller
Dong Bo Li
Denise Vogel
Nicole Westerfeld
Rinaldo Zurbriggen
John A Robinson
Gerd Pluschke
method:
immuno staining
name:
Antibodies elicited by a virosomally formulated Plasmodium falciparum serine repeat antigen-5 derived peptide detect the processed 47 kDa fragment both in sporozoites and merozoites.
description:
Mice immunized with the epitope conjugated to immunopotentiating reconstituted influenza virosomes (IRIV) generated antibodies that reacted with blood stage parasite-infected erythrocytes in IFA. Only epitope 57-94 elicited IFA and western blotting titers >100 in all immunized mice. Four lysine residues added to this peptide to improve solubility, did not significantly impact immunogenicity.

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