Immunological Data Discovery Index
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  1. Humoral and Cell-Mediated Immune Responses to Vaccinia Virus Immunization ImmuneSpace

    ID: SDY28

    Description: Our broad objective is to examine the role of candidate human immune response gene polymorphisms (and their receptors, expression and function) in int...

    Publication: 23594957; ; 23806267; ; 27513748; ; 22949304; ; 19038260;
  2. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes ImmuneSpace

    ID: SDY207

    Description: High dimensional analysis of CD8+ T cell phenotype and function

    Publication: 22265676;
  3. TIV 2008 vaccination of CD95-/- mice and ELISA for detection of influenza-specific antibodies ImmuneSpace

    ID: SDY215

    Description: Evaluation of the mouse immune response to influenza vaccination. ELISA was used to examine the immune response of mutant mice (MRL/Mpj-Faslpr/J (Mpj...

    Publication: 23591775;
  4. Systems Biology Analysis of the response to Licensed Hepatitis B Vaccine (HEPLISAV) in Whole Blood (see companion studies SDY816 and SDY690) ImmuneSpace

    ID: SDY299

    Description: This project will contribute to the overall vision and goals of this U19 by analyzing the role of adjuvants in the humoral response to hep B vaccinati...

  5. T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination (TIV) - 2008 (See companion studies SDY315 2012 / SDY312 2009 / S... ImmuneSpace

    ID: SDY314

    Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

  6. Systems Biology Approach to Study Influenza Vaccine 2013-14 in Healthy Children (see companion studies SDY364, SDY144, SDY387) ImmuneSpace

    ID: SDY368

    Description: The treatment of pediatric immune system dysfunctions depends upon the basic understanding of its molecular and cellular components, as well as the in...

  7. B and T Cell Determinants of Influenza Vaccine Responses in the Elderly 2008 (see companion study SDY773) ImmuneSpace

    ID: SDY460

    Description: Application of high-throughput DNA sequencing of the IGH gene rearrangements to study the B cell repertoires over two successive years in 27 individua...

    Publication: 24337376;
  8. CMV CD8 T Cells ImmuneSpace

    ID: SDY1041

    Description: We present human T cell responses in multiple sites including blood, lymphoid, mucosal and secretory tissues of 20 CMV seropositive donors. Overall, C...

    Publication: 28130404;
  9. Early-life compartmentalization of human T cells ImmuneSpace

    ID: SDY1097

    Description: Knowledge of human immune responses during early life remains sparse, owing to the difficulty and impracticality of obtaining blood and tissue samples...

    Publication: 26657141;
  10. CD4 Nicaragua Epitope ID ImmuneSpace

    ID: SDY1109

    Description: We performed DENV-specific epitope screening studies in the general population of Managua. Peptides with the capacity to bind HLA DR molecules most c...

  11. Immunologic and genomic signatures of influenza vaccine response - 2010 (see companion studies SDY400, SDY404, SDY520) ImmuneSpace

    ID: SDY63

    Description: Project 1: Immunologic and genomic signatures of influenza vaccine response.

  12. Systems Biology Approach to Analysis of 2010-11 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY301, SDY296) ImmuneSpace

    ID: SDY74

    Description: This study will measure the immune response to the influenza vaccine The long-term goal is to develop improved vaccines to infectious diseases such a...

    Publication: 23486778;
  13. Cellular and molecular characterization of the immune response in healthy NIH employees at baseline and after immunization with the H1N1 or seasonal i... ImmuneSpace

    ID: SDY80

    Description: The Center for Human Immunology, Autoimmunity, and Inflammatory Diseases proposes this protocol designed to obtain blood from healthy adult subjects (...

    Publication: 24725414;
  14. Systems Biology Approach to Analysis of 2011-12 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY74, SDY301) ImmuneSpace

    ID: SDY296

    Description: This project will contribute to the overall vision and goals of this U19 by analyzing the immune response to Flu vaccination in healthy individuals. T...

  15. Systems Biology Approach to Analysis of 2012-13 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY74, SDY296) ImmuneSpace

    ID: SDY301

    Description: This project will contribute to the overall vision and goals of this U19 by analyzing the immune response to Flu vaccination in healthy individuals. T...

  16. Plasmablast response to inactivated and live attenuated influenza vaccines (TIV3/TIV3 ID) in 2012 ImmuneSpace

    ID: SDY305

    Description: To study the plasmablast response to 2012 seasonal inactivated influenza vaccine

  17. Immunologic and genomic signatures of influenza vaccine response - 2011 (see companion studies SDY63, SDY400, SDY520) ImmuneSpace

    ID: SDY404

    Description: Project 1: Immunologic and genomic signatures of influenza vaccine response - year2 2011

    Publication: 25367297;
  18. Immune Responses to Influenza-Like Illness ImmuneSpace

    ID: SDY406

    Description: To investigate the nasal transcriptional response and peripheral plasmablast response in acute influenza infection

  19. Plasmablast response to inactivated and live attenuated influenza vaccines (TIV3/TIV3 ID) in 2013 ImmuneSpace

    ID: SDY472

    Description: This study will be conducted with up to 40 generally healthy children

  20. Humoral responses to West Nile virus ImmuneSpace

    ID: SDY508

    Description: Integrate two high-throughput technologies namely, microengraving-based screening of primary B cells and next-generation sequencing to examine the rel...

  21. Differences in Antibody Responses Between Trivalent Inactivated Influenza Vaccine and Live Attenuated Influenza Vaccine (2011-12) Correlate With the K... ImmuneSpace

    ID: SDY522

    Description: The treatment of pediatric immune system dysfunctions depends upon the basic understanding of its molecular and cellular components, as well as the in...

    Publication: 24495909;
  22. Mayo Clinic Smallpox Vaccine Immunogenetics Replication Study ImmuneSpace

    ID: SDY614

    Description: Smallpox Vaccine Immunogenetics

    Publication: 28158231; ; 22542470;
  23. Human Immune Signature of latent TB infection ImmuneSpace

    ID: SDY820

    Description: The human immune signature of latent Mycobacterium tuberculosis infected patients as well as BCG vaccinated and BCG non-vaccinated individuals was stu...

    Publication: 28069807;
  24. Comparison of immune response to influenza vaccine in transplant patients and healthy controls ImmuneSpace

    ID: SDY34

    Description: This is a prospective longitudinal study to determine the effects of chronic immunosuppressive therapies on the magnitude and character of the adaptiv...

    Publication: 19247287; ; 21220454; ; 18449194;
  25. Systems Biology of 2007 Influenza Vaccination in Humans (See companion studies SDY269 2008 / SDY270 2009 / SDY271 Role for CaMKIV in the Regulation of... ImmuneSpace

    ID: SDY61

    Description: Using a systems biology approach to study innate and adaptive responses to influenza vaccination in humans during the 2007-2008 influenza season.

    Publication: 21743478; ; 26682988;
  26. Bioinformatics Approach to 2010-2011 TIV Influenza A/H1N1 Vaccine Immune Profiling ImmuneSpace

    ID: SDY67

    Description: Aim 1: Characterize Immune Profiles Over Time, Aim 2: Correlate Immune Profiles with Vaccine Immunogenicity,Aim 3: Replication of Immune Profiles and ...

    Publication: 27441275; ; 25816015; ; 27031986;
  27. Plasmablast response to inactivated and live attenuated influenza vaccines (TIV3/TIV3 ID/LAIV) in 2011 ImmuneSpace

    ID: SDY113

    Description: To study the plasmablast response to influenza vaccines

    Publication: 24676204;
  28. Systems Biology Approach to Study Influenza Vaccine 2011-12 in Healthy Children (see companion studies SDY364, SDY368, SDY387) ImmuneSpace

    ID: SDY144

    Description: The treatment of pediatric immune system dysfunctions depends upon the basic understanding of its molecular and cellular components, as well as the in...

    Publication: 24495909;
  29. Systems Biology of 2008 Influenza Vaccination in Humans (See companion studies SDY61 2007 / SDY270 2009 / SDY271 Role for CaMKIV in the Regulation of ... ImmuneSpace

    ID: SDY269

    Description: Using a systems biology approach to study innate and adaptive responses to influenza vaccination in humans during the 2008-2009 influenza season.

    Publication: 26682988; ; 21743478;
  30. Optimization FACS panels ImmuneSpace

    ID: SDY278

    Description: Optimization of ICS and phenotyping panels for the Mal067 study using cryopreserved PBMC samples from the SAC cohort

  31. Immune Responses to Influenza-Like Illness ImmuneSpace

    ID: SDY395

    Description: To investigate the nasal transcriptional response and peripheral plasmablast response in acute influenza infection

  32. Immunologic and genomic signatures of influenza vaccine response - 2012 (see companion studies SDY63, SDY404, SDY520) ImmuneSpace

    ID: SDY400

    Description: Project 1: Immunologic and genomic signatures of influenza vaccine response - year3 2012

  33. Clonal B cell response to naturally occurring pathogens causing tissue specific immune responses in human ImmuneSpace

    ID: SDY421

    Description: Elucidate the trafficking specificity, or diversity, of clonal B cell responses to mucosae-associated illnesses or infections in vivo.

  34. DFCI HLA typing ImmuneSpace

    ID: SDY422

    Description: We used an in situ synthesized DNA-based microarray method that contains thousands of probes representing a complete overlapping set covering 1,610 cl...

    Publication: 25505899;
  35. Monitoring of tissue-specific immune responses in man to naturally occurring pathogens using mass cytometric monitoring ImmuneSpace

    ID: SDY461

    Description: Elucidate the trafficking specificity, or diversity, of clonal B cell responses to mucosae-associated illnesses or infections in vivo.

  36. T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination - 2013 ImmuneSpace

    ID: SDY478

    Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

  37. Monozygotic and Dizygotic Twin Pair T-Cell Responses to Influenza Vaccination 2009 ImmuneSpace

    ID: SDY514

    Description: Evaluate the variation in immune response between individuals and assess whether it changes as a function of age and similarity in genetic and environ...

    Publication: 25594173;
  38. Immunologic and genomic signatures of influenza vaccine response - 2013 (see companion studies SDY63, SDY404, SDY400) ImmuneSpace

    ID: SDY520

    Description: Project 1: Immunologic and genomic signatures of influenza vaccine response - year4 2013

  39. DC transcriptomics in response to vaccines ImmuneSpace

    ID: SDY597

    Description: The mechanisms by which microbial vaccines interact with human APCs remain elusive.

    Publication: 25335753;
  40. The immune signature of palmoplantar pustulosis ImmuneSpace

    ID: SDY667

    Description: This study will compare adult patients with CPP(chronic plaque type psoriasis ), who are currently not undergoing topical, systemic or biologic treatm...

  41. Heritable influence on the B and T cell receptor repertoire ImmuneSpace

    ID: SDY675

    Description: The adaptive immune systems capability to protect the body requires a highly diverse lymphocyte antigen receptor repertoire. However, the influence of...

    Publication: 27005435;
  42. Histology post influenza ImmuneSpace

    ID: SDY756

    Description: Histological analysis in lung post infection of B6 or B6 A02 transgenic AAD mice with influenza A/PR8/34 virus

  43. Immunity to Smallpox Vaccination ImmuneSpace

    ID: SDY18

    Description: We propose to put together a program that combines one of the largest collections of recorded vaccine responses in the world with our extensive geneal...

  44. Systems Biology of trivalent Influenza vaccine (TIV) in young and elderly ImmuneSpace

    ID: SDY56

    Description: Study ObjectiveTo identify innate signatures that correlate with the magnitude, quality and persistence of B cell responses after vaccination with TIV...

  45. In-Depth Characterization of Immune Responses to Pneumovax Vaccination in Healthy Subjects ImmuneSpace

    ID: SDY87

    Description: This study will measure the immune response to the Pneumovax vaccine The long-term goal is to develop improved vaccines to infectious diseases such a...

  46. T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination (TIV) - 2011 (See companion studies SDY311 2010 / SDY312 2009 / S... ImmuneSpace

    ID: SDY112

    Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

  47. Immunologic and genomic signatures of response to Hepatitis C Virus infection. ImmuneSpace

    ID: SDY162

    Description: Examine the immune response in primary immune cells from subjects who have spontaneously cleared HCV compared to HCV chronically infected subjects

    Publication: 23220997;
  48. VRC304 - A Phase I Study of the Safety and Immunogenicity of a Recombinant DNA Plasmid Vaccine (VRC-AVIDNA036-00-VP) Encoding for the Influenza Virus ... ImmuneSpace

    ID: SDY167

    Description: The primary objective was to evaluate the safety and tolerability of an investigational vaccine VRC-AVIDNA036-00-VP in humans at doses 1 mg and 4 mg a...

    Publication: 22956656;
  49. Apoptosis and other immune biomarkers predict influenza vaccine (TIV 2008) responsiveness ImmuneSpace

    ID: SDY212

    Description: Despite the importance of the immune system in many diseases, there are currently no objective benchmarks of immunological health. In an effort to ind...

    Publication: 24337376; ; 27746093; ; 23591775;
  50. Systems Biology of 2009 Influenza Vaccination in Humans (See companion studies SDY61 2007 / SDY269 2008 / SDY271 Role for CaMKIV in the Regulation of ... ImmuneSpace

    ID: SDY270

    Description: Using a systems biology approach to study innate and adaptive responses to influenza vaccination in humans during the 2009-2010 influenza season.

    Publication: 21743478; ; 26682988;

Displaying 50 of 74 results for " "