Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | SDY283 |
| description: |
The study performed expression microarrays on RNA from purified subsets of neonatal and adult APCs, which were stimulated or not stimulated with a TLR ligands of interest. Arrays were performed on cells from neonatal and adult individuals, and the arrays for all will be run in parallel on the same day. This study used ELISA to assess the abundance and activation induced modifications of relevant TLRs, adaptors and downstream signaling pathway components.
|
| aggregation: |
instance of dataset
|
| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
|
| availability: |
available with registration
|
| isAbout: |
To explore the molecular mechanism(s) for TLR ligand response differences between adults and neonates and to assess abundance and activation induced modifications of relevant TLRs, adaptors and downstream signaling pathway components.
|
| authorizations: |
registration required
|
| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY283 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY283 |
| clinical trial: | |
| study category: | Immune Response |
| study type: | Observational |
| subject species: | Homo sapiens |
| biosample type: | Cell |
| subject gender: | Not Specified |
| assay type: | ELISA |
| name: |
Cell mediated immune response mechanisms.
|
| fullName: |
Christopher Wilson
|
| affiliations: |
University of Washington
|
| roles: |
principal investigator
|
| name: |
Exploration of molecular mechanism(s) for TLR ligand response differences between adults and neonates
|
| size: |
89
|
| name: |
TLRs in Innate Immunity and the Induction of Adaptive Immunity in the Neonate and Infant
|
| output: |
ELISA
|
| studyGroups: |
Neonate human: Neonate human
Adult human: Adult human
|
| description: |
The study will perform expression microarrays on RNA from purified subsets of neonatal and adult APCs either stimulated or not stimulated with TLR ligands of interest. Arrays will be performed on cells from neonatal and adult individuals and the arrays for all will be run in parallel on the same day.
|
| identifier: |
10.21430/M30USX09NF
|
| name: |
ImmPort
|
| identifier: |
SCR:012804
|
| homePage: |
http://www.immport.org |
