| identifier: | SDY753 |
| description: |
The goal of this proposal is to characterize alterations to the nasal microbiome after vaccination with the 2012-2013 seasonal LAIV and to correlate these changes with LAIV-specific immune responses (A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2)).
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| isAbout: |
Specific Aim 1: Measure changes in the nasal microbiome after vaccination with LAIV using high-throughput sequencing analysis of 16S rRNA genes; Correlate baseline and changes to the nasal microbiome after vaccination with LAIV vaccination with inter-individual differences in influenza-specific mucosal immune responses
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| authorizations: |
registration required
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| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY753 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY753 |
| clinical trial: | |
| study category: | Vaccine Response |
| study type: | Interventional |
| subject species: | Homo sapiens |
| biosample type: |
DNA Other |
| subject gender: | Both |
| assay type: |
ELISA Sequencing |
| name: |
A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2))
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| fullName: |
Gregory Poland
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| affiliations: |
Mayo Clinic
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| roles: |
principal investigator
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| name: |
Investigating Alterations to the Nasal Microbiome after Vaccination with LAIV
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| size: |
47
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| name: |
Bioinformatics Approach to Influenza A/H1N1 Vaccine Immune Profiling
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| output: |
HA1 (H1N1/H3N2)
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| studyGroups: |
healthy young adults: 47 healthy adults age 18-30
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| description: |
Microbiome alteration in response to influenza vaccine
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| identifier: |
10.21430/M3ENN2D3SZ
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| startDate: |
2013-01-01
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| name: |
ImmPort
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| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |