Immunological Data Discovery Index
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identifier: SDY753
description:
The goal of this proposal is to characterize alterations to the nasal microbiome after vaccination with the 2012-2013 seasonal LAIV and to correlate these changes with LAIV-specific immune responses (A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2)).
aggregation:
instance of dataset
refinement:
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
availability:
available with registration
isAbout:
Specific Aim 1: Measure changes in the nasal microbiome after vaccination with LAIV using high-throughput sequencing analysis of 16S rRNA genes; Correlate baseline and changes to the nasal microbiome after vaccination with LAIV vaccination with inter-individual differences in influenza-specific mucosal immune responses
clinical trial:
study category: Vaccine Response
study type: Interventional
subject species: Homo sapiens
biosample type: DNA
Other
subject gender: Both
assay type: ELISA
Sequencing
name:
A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2))
fullName:
Gregory Poland
affiliations:
Mayo Clinic
roles:
principal investigator
name:
Investigating Alterations to the Nasal Microbiome after Vaccination with LAIV
size:
47
name:
Bioinformatics Approach to Influenza A/H1N1 Vaccine Immune Profiling
output:
HA1 (H1N1/H3N2)
studyGroups:
healthy young adults: 47 healthy adults age 18-30
description:
Microbiome alteration in response to influenza vaccine
identifier:
10.21430/M3ENN2D3SZ
startDate:
2013-01-01
name:
ImmPort
identifier:
SCR:012804
homePage: http://www.immport.org

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