Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | SDY7 |
| description: |
To measure total and specific antibody titers and T cell responses in a sample of subjects who experienced eczema vaccinatum (EV) and a group of subjects who did not suffer from EV (normal controls or healthy AD subjects).
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| isAbout: |
To measure Vaccinia antibody titers and T cell responses in subjects who experienced EV and a group of subjects who did not suffer from EV (NA controls or AD subjects).
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| authorizations: |
registration required
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| accessURL: |
http://clinicaltrials.gov/ct2/show/study/NCT00550316 https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY7 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY7 |
| clinical trial: | clinical trial |
| study category: | Atopy/Allergy |
| study type: | Observational |
| subject species: | Homo sapiens |
| biosample type: | Other |
| subject gender: | Both |
| assay type: |
| name: |
Atopic Dermatitis Eczema Vaccinatum
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| fullName: |
Donald Leung
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| affiliations: |
National Jewish Health
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| roles: |
principal investigator
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| name: |
ADVN Biomarker Registry Study: CMI/Ab-Vaccinia Substudy
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| size: |
90
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| name: |
Atopic Dermatitis & Vaccinia Network (ADVN) Clinical Studies Consortium
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| output: |
Total antibodies (ELISA)
Total vaccinia-specific antibodies (ELISA)
Neutralizing antiviral serum vaccinia-specific antibodies (plaque reduction assay)
Vaccinia-specific memory B-cells (limiting dilution analysis)
IFNγ production by vaccinia-specific CD4+ T cells
IFNγ production by vaccinia-specific CD8+ T cells
IFNγ production by vaccinia-specific NK T cells
CD3 cytokine responses from Memory T cells (Pos Control)
Antigen specific antibody levels: diphtheria
Antigen specific antibody levels: tetanus
Antigen specific antibody levels: pertussis
Antigen specific antibody levels: measles
Antigen specific antibody levels: mumps
Antigen specific antibody levels: rubella
Antigen specific antibody levels: polio
Antigen specific antibody levels: varicella
Antigen specific antibody levels: Epstein-Barr
Antigen specific antibody levels: cytomegalovirus
Total IgE
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| studyGroups: |
AD+ EV+ with vaccination: Atopic Dermatitis subjects with previous or current EV eczema vaccinatum after smallpox vaccination.
AD+ EV- with vaccination: Atopic Dermatitis subjects with no EV after smallpox vaccination.
Healthy controls with vaccination: Nonatopic/healthy subjects and no eczema vaccinatum after smallpox vaccination.
AD+ no vaccination: Atopic Dermatitis subjects, no smallpox vaccinations.
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| description: |
To measure total and specific antibody titers and T cell responses in a sample of subjects who experienced eczema vaccinatum (EV) and a group of subjects who did not suffer from EV (normal controls or healthy AD subjects).
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| identifier: |
10.21430/M3G81PA5G7
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| startDate: |
2008-04-01
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| name: |
ImmPort
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| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |
