| Title: | Human Aging and CMV |
| identifier: | SDY736 |
| description: |
Delineate the effect of aging from that of cytomegalovirus (CMV) infection upon relative and absolute changes in blood T cell subsets using a cohort of 391 individuals ranging in age from 21-101yrs, seperated into two subgroups based on serological CMV status.
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| primaryPublications: |
24501199 27270402 |
| isAbout: |
Determine the distinct roles of chronological aging as well as prior CMV infection on the absolute changes in blood T cell subsets.
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| authorizations: |
registration required
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| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY736 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY736 |
| clinical trial: | |
| study category: | Immune Response |
| study type: | Observational |
| subject species: | Homo sapiens |
| biosample type: |
PBMC Plasma Whole blood |
| subject gender: | Female, Male, Unknown |
| assay type: | Flow Cytometry |
| name: |
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans
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| fullName: |
Janko Nikolich-Zugich
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| affiliations: |
University of Arizona
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| roles: |
principal investigator
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| name: |
Human Aging and CMV
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| size: |
393
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| name: |
Immunological basis of age-related vulnerability in biodefense and emerging infections SP2 UAz
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| output: |
Flow cytometry for Tcell phenotype, ELISA for CMV serology
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| studyGroups: |
CMV positive: These donors were found to be seropositive for cytomegalo virus (CMV)
CMV negative: These donors were found to be sero-negative for cytomegalo virus (CMV)
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| description: |
Delineate the effect of aging from that of cytomegalovirus (CMV) infection upon relative and absolute changes in blood T cell subsets.
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| identifier: |
10.21430/M3736K8GMY
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| startDate: |
2015-04-21
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| name: |
ImmPort
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| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |