Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | HP47 |
| identifier: | SDY601 |
| description: |
WT and PPARgfl/fl:LysCre+ (R2+) mice were infected with 5x10e7 CFU of different Helicobacter pylori strains (26695, SS1 and PMSS1). A control uninfected group was included for each genotype. Tissues were collected at 9 months post-infection to determine bacterial loads (stomach) and to assess the expansion of CD4 and CD8 T cells, macrophages, dendritic cells and neutrophils by flow cytometry (blood, spleen and stomach).
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| isAbout: |
To compare the long-term bacterial loads and induction of immune responses by different Helicobacter pylori strains (SS1, PMSS1 and 26695)
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| authorizations: |
registration required
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| accessURL: |
http://www.modelingimmunity.org/ https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY601 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY601 |
| clinical trial: | |
| study category: |
Immune Response Infection Response |
| study type: | Longitudinal |
| subject species: | Mus musculus |
| biosample type: | Tissue |
| subject gender: | Both |
| assay type: |
Flow Cytometry Other |
| name: |
Helicobacter pylori infection
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| fullName: |
Josep Bassaganya-Riera
Raquel Hontecillas
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| affiliations: |
NIMML
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| roles: |
principal investigator
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| name: |
HP47
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| size: |
426
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| name: |
Virginia Bioinformatics Institute Modeling Immunity for Biodefense Contract
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| output: |
Mice were euthanized at 9 months post-infection to assess bacterial loads and immune cell populations by flow cytometry
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| studyGroups: |
H. pylori 26695: H. pylori 26695
H. pylori SS1: H. pylori SS1
H. pylori PMSS1: H. pylori PMSS1
Uninfected: Uninfected
H. pylori SS1 (Case): H. pylori SS1 (Case)
Uninfected (Control): Uninfected (Control)
H. pylori SS1 5X10e6: H. pylori SS1 5X10e6
H. pylori SS1 5X10e7: H. pylori SS1 5X10e7
H. pylori SS1 5x10e5: H. pylori SS1 5x10e5
H. pylori SS1 5x10e8: H. pylori SS1 5x10e8
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| description: |
WT and PPARgfl/fl:LysCre+ (R2+) mice were infected with 5x10e7 CFU of different Helicobacter pylori strains (26695, SS1 and PMSS1). A control uninfected group was included for each genotype. Tissues were collected at 9 months post-infection to determine bacterial loads (stomach) and to assess the expansion of CD4 and CD8 T cells, macrophages, dendritic cells and neutrophils by flow cytometry (blood, spleen and stomach).
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| identifier: |
10.21430/M3SB5VLQDV
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| startDate: |
2014-04-15
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| name: |
ImmPort
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| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |