Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | SDY63 |
| description: |
Project 1: Immunologic and genomic signatures of influenza vaccine response.
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| isAbout: |
Identification of immunologic, gene expression, and genetic loci signatures of vaccine response, and effects of aging and functional status on these signatures.
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| authorizations: |
registration required
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| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY63 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY63 |
| clinical trial: | |
| study category: | Vaccine Response |
| study type: | Observational |
| subject species: | Homo sapiens |
| biosample type: |
Cell PBMC Whole blood |
| subject gender: | Both |
| assay type: |
DNA microarray Hemagglutination Inhibition |
| name: |
Immunologic and genomic signatures of influenza vaccine response
|
| fullName: |
David Hafler
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| affiliations: |
Yale
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| roles: |
principal investigator
|
| name: |
Immunologic and genomic signatures of influenza vaccine response - 2010 (see companion studies SDY400, SDY404, SDY520)
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| size: |
49
|
| name: |
Defining signatures for immune responsiveness by functional systems immunology HIPC1
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| output: |
B cells (ASC, Memory); T cells (Ag specific CD8 and CD4, memory T cell subsets, Tregs, exhausted/senescent); in vitro activation of flu-specific T cells; Monocyte/DC stim by flu or through TLRs; innate cell TLR expression; Luminex assays of cytokines post vaccine; Illumina HT12 bead chip and Nanostring.
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| studyGroups: |
Young adults 21-30 years old: Young adults 21-30 years old
Older adults >= 65 years old: Older adults >= 65 years old
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| description: |
Project 1: Immunologic and genomic signatures of influenza vaccine response.
|
| identifier: |
10.21430/M38WXGBDTS
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| name: |
ImmPort
|
| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |
