| identifier: | SDY585 |
| description: |
Study of Influenza vaccine coupled with adjuvant in Murine model
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| aggregation: |
instance of dataset
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| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
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| availability: |
available with registration
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| isAbout: |
Design and conduct in vivo murine experiments with X31(H3N2) infection primed and purified inactivated A/Port Chalmers/1/73 (H3N2) whole virus with MF59-like adjuvant boosted mice to build, identify and experimentally validate the proposed immune response models by generating high frequency sampling and high dimensional datasets.
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| authorizations: |
registration required
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| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY585 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY585 |
| clinical trial: | |
| study category: | Vaccine Response |
| study type: | Interventional |
| subject species: | Mus musculus |
| biosample type: |
Lymph node Other PBMC Spleen |
| subject gender: | Female |
| assay type: |
ELISPOT Flow Cytometry |
| name: |
Immune response in mouse model
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| fullName: |
Martin Zand
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| affiliations: |
University of Rochester Center for Biodefense Immune Modeling
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| roles: |
principal investigator
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| name: |
2013 Murine Vaccine with Adjuvant Study
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| size: |
36
|
| name: |
University of Rochester Center for Biodefense Immune Modeling II
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| output: |
Blood, spleen, bone marrow and lymph node samples prior to prime, prior to boosting with influenza vaccine with adjuvant and daily sampling up to 10 days post boosting.
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| studyGroups: |
Murine vaccine with adjuvant run: Mice primed with X31 (H3N2) intranasal infection followed by an intramuscular boost with purified inactivated A/Port Chalmers/1/73 (H3N2) whole virus with MF59-like adjuvant.
|
| description: |
Study of Influenza vaccine coupled with adjuvant in Murine model
|
| identifier: |
10.21430/M3I8W54C3M
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| startDate: |
2013-07-18
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| name: |
ImmPort
|
| identifier: |
SCR:012804
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| homePage: |
http://www.immport.org |