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identifier: SDY585
description:
Study of Influenza vaccine coupled with adjuvant in Murine model
aggregation:
instance of dataset
refinement:
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
availability:
available with registration
isAbout:
Design and conduct in vivo murine experiments with X31(H3N2) infection primed and purified inactivated A/Port Chalmers/1/73 (H3N2) whole virus with MF59-like adjuvant boosted mice to build, identify and experimentally validate the proposed immune response models by generating high frequency sampling and high dimensional datasets.
clinical trial:
study category: Vaccine Response
study type: Interventional
subject species: Mus musculus
biosample type: Lymph node
Other
PBMC
Spleen
subject gender: Female
assay type: ELISPOT
Flow Cytometry
name:
Immune response in mouse model
fullName:
Martin Zand
affiliations:
University of Rochester Center for Biodefense Immune Modeling
roles:
principal investigator
name:
2013 Murine Vaccine with Adjuvant Study
size:
36
name:
University of Rochester Center for Biodefense Immune Modeling II
output:
Blood, spleen, bone marrow and lymph node samples prior to prime, prior to boosting with influenza vaccine with adjuvant and daily sampling up to 10 days post boosting.
studyGroups:
Murine vaccine with adjuvant run: Mice primed with X31 (H3N2) intranasal infection followed by an intramuscular boost with purified inactivated A/Port Chalmers/1/73 (H3N2) whole virus with MF59-like adjuvant.
description:
Study of Influenza vaccine coupled with adjuvant in Murine model
identifier:
10.21430/M3I8W54C3M
startDate:
2013-07-18
name:
ImmPort
identifier:
SCR:012804
homePage: http://www.immport.org

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