| identifier: | SDY667 |
| description: |
This study will compare adult patients with CPP(chronic plaque type psoriasis ), who are currently not undergoing topical, systemic or biologic treatment and matched healthy controls. Baseline demographics and psoriasis history will be recorded. All PPP patients will be comprehensively phenotyped and psoriasis severity assessed including the body surface area (BSA) involved, Psoriasis Area and Severity Index (PASI), Physicians Global assessment (PGA) and Dermatology Life Quality Index (DLQI).
|
| aggregation: |
instance of dataset
|
| refinement: |
2 - Complete set of descriptive data and results, as ascertained by ImmPort.
|
| availability: |
available with registration
|
| isAbout: |
To identify transcriptional signatures in the blood of patients with palmoplantar pustulosis (PPP) and their modulation through in vivo stimulation with vaccination.
|
| authorizations: |
registration required
|
| accessURL: |
https://aspera-immport.niaid.nih.gov:9443/browser?path=SDY667 |
| landingPage: |
http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY667 |
| clinical trial: | |
| study category: | Vaccine Response |
| study type: | Observational |
| subject species: | Homo sapiens |
| biosample type: | Whole blood |
| subject gender: | Both |
| assay type: | DNA microarray |
| name: |
Patients with PPP compared to healthy controls (recruited also at the derm clinic).In addition, archived samples from healthy donors and patients with chronic plaque type psoriasis (CPP) will be included
|
| fullName: |
Gerlinde Obermoser
|
| affiliations: |
Baylor Institute for Immunology research
|
| roles: |
principal investigator
|
| name: |
The immune signature of palmoplantar pustulosis
|
| size: |
50
|
| name: |
Systems Analysis Vaccine Responses in Healthy and Hyporesponsive Humans
|
| output: |
This study will compare adult patients with CPP, who are currently not undergoing topical, systemic or biologic treatment and matched healthy controls
|
| studyGroups: |
HIPC-PSOR-PPP: Subjects are age 18 years or older, with a diagnosis of palmoplantar pustulosis (PPP)
|
| description: |
This study will compare adult patients with CPP(chronic plaque type psoriasis ), who are currently not undergoing topical, systemic or biologic treatment and matched healthy controls. Baseline demographics and psoriasis history will be recorded. All PPP patients will be comprehensively phenotyped and psoriasis severity assessed including the body surface area (BSA) involved, Psoriasis Area and Severity Index (PASI), Physicians Global assessment (PGA) and Dermatology Life Quality Index (DLQI).
|
| identifier: |
10.21430/M34NBAVDGJ
|
| startDate: |
2010-11-01
|
| name: |
ImmPort
|
| identifier: |
SCR:012804
|
| homePage: |
http://www.immport.org |