| identifier: | SDY404 |
| description: |
Project 1: Immunologic and genomic signatures of influenza vaccine response - year2 2011
|
| aggregation: |
instance of dataset
|
| availability: |
available with registration
|
| acknowledges: |
NIAID (HIPC funded)
|
| primaryPublications: |
25367297 |
| isAbout: |
Identification of immunologic, gene expression, and genetic loci signatures of vaccine response, and effects of aging and functional status on these signatures.
|
| authorizations: |
registration required
|
| types: |
Hemagglutination inhibition (HAI)
FCS control files
FCS sample files
Gene expression microarray data files
|
| accessURL: |
https://www.immunespace.org/study/Studies/SDY404/dataset.view?datasetId=5005 https://www.immunespace.org/study/Studies/SDY404/dataset.view?datasetId=5019 https://www.immunespace.org/study/Studies/SDY404/dataset.view?datasetId=5018 https://www.immunespace.org/study/Studies/SDY404/dataset.view?datasetId=5014 |
| landingPage: |
https://www.immunespace.org/project/Studies/SDY404/begin.view? |
| subject species: | Homo sapiens |
| study conditions: | Influenza |
| study type: | Observational |
| study category: | Vaccine Response |
| assay type: |
Gene Expression HAI |
| time point: |
15-27 29-55 |
| subject race: |
Asian Black or African American Other Unknown White |
| subject gender: |
Female Male |
| subject age: |
21-30 31-40 61-70 > 70 |
| name: |
Immunologic and genomic signatures of influenza vaccine response
|
| affiliations: |
Yale
|
| fullName: |
David Hafler
|
| roles: |
principal investigator
|
| name: |
Immunologic and genomic signatures of influenza vaccine response - 2011 (see companion studies SDY63, SDY400, SDY520)
|
| size: |
72
|
| output: |
B cells (ASC, Memory); T cells (Ag specific CD8 and CD4, memory T cell subsets, Tregs, exhausted/senescent); in vitro activation of flu-specific T cells; Monocyte/DC stim by flu or through TLRs; innate cell TLR expression; Luminex assays of cytokines post vaccine; Illumina HT12 bead chip and Nanostring.
|
| description: |
Project 1: Immunologic and genomic signatures of influenza vaccine response - year2 2011
|
| name: |
ImmuneSpace
|
| homePage: |
http://www.immunespace.org |