Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | SDY753 |
| description: |
The goal of this proposal is to characterize alterations to the nasal microbiome after vaccination with the 2012-2013 seasonal LAIV and to correlate these changes with LAIV-specific immune responses (A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2)).
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| aggregation: |
instance of dataset
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| availability: |
available with registration
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| acknowledges: |
NIAID (HIPC funded)
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| isAbout: |
Specific Aim 1: Measure changes in the nasal microbiome after vaccination with LAIV using high-throughput sequencing analysis of 16S rRNA genes; Correlate baseline and changes to the nasal microbiome after vaccination with LAIV vaccination with inter-individual differences in influenza-specific mucosal immune responses
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| authorizations: |
registration required
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| types: |
Hemagglutination inhibition (HAI)
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| accessURL: |
https://www.immunespace.org/study/Studies/SDY753/dataset.view?datasetId=5005 |
| landingPage: |
https://www.immunespace.org/project/Studies/SDY753/begin.view? |
| subject species: | Homo sapiens |
| study conditions: | Other |
| study type: | Interventional |
| study category: | Vaccine Response |
| assay type: | HAI |
| time point: | 29-55 |
| subject race: |
Black or African American Other White |
| subject gender: |
Female Male |
| subject age: |
11-20 21-30 31-40 |
| name: |
A/California/7/2009 (H1N1) and A/Victoria/361/2011 (H3N2))
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| affiliations: |
Mayo Clinic
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| fullName: |
Gregory Poland
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| roles: |
principal investigator
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| name: |
Investigating Alterations to the Nasal Microbiome after Vaccination with LAIV
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| size: |
47
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| output: |
HA1 (H1N1/H3N2)
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| description: |
Microbiome alteration in response to influenza vaccine
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| name: |
ImmuneSpace
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| homePage: |
http://www.immunespace.org |
