Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection.
identifier: 1464692
description:
epitope description:SLKMADPNRFRGKDLP
antigen name:Envelope glycoprotein D
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 14505924
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1007133
landingPage: http://www.iedb.org/assay/1464692
type:
Literature
publicationVenue:
Vaccine
dates:
2003
study type: b cell assays
subject species: Human alphaherpesvirus 1
fullName:
N Goel
Q Rong
D Zimmerman
K S Rosenthal
method:
ELISA
name:
A L.E.A.P.S. heteroconjugate vaccine containing a T cell epitope from HSV-1 glycoprotein D elicits Th1 responses and protection.
description:
The L.E.A.P.S.TM heteroconjugate vaccine antigen, composed of this T cell epitope from glycoprotein D of herpes simplex virus linked with a peptide sequence from beta-2-microglobulin, elicited protection against lethal intraperitoneal challenge. The sera from animals surviving this experiment were subjected to isotype analysis for antibody specific for HSV-infected cell extract. The IgG2a/IgG1 ratio was >1, indicative of a Th1 response.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston