Identification of the amino acid residues in trichosanthin crucial for IgE response. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Identification of the amino acid residues in trichosanthin crucial for IgE response.

Dataset

identifier:	1465532
description:	epitope description:QQIGKR antigen name:Ribosome-inactivating protein alpha-trichosanthin host organism:Mus musculus antibody name:TE1
aggregation:	instance of dataset
availability:	available
primaryPublications:	12270124

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005464
landingPage:	http://www.iedb.org/assay/1465532

Publication

type:	Literature
publicationVenue:	Biochem Biophys Res Commun
dates:	2002

Dimension

study type:	b cell assays
subject species:	Trichosanthes kirilowii

Person

fullName:	Xuan Cai Gang Yao Guofeng Xu Cuihong Yang Hong Xu Ying Lin Jian Yu Bing Sun

Data Type

method:	western blot

Study

name:	Identification of the amino acid residues in trichosanthin crucial for IgE response.
description:	This epitope was deduced by panning a phage display library with the mAb TE1 Epitope specific antibody(ies) bound wild type trichosanthin, but not mutant protein with substitutions in amino acid residues 5 and 6 of the epitope, indicating that these are the critical residues.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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