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identifier: 1465684
description:
epitope description:EEEDDD
antigen name:Other Trypanosoma cruzi protein
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 9562426
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1005206
landingPage: http://www.iedb.org/assay/1465684
type:
Literature
publicationVenue:
Exp Parasitol
dates:
1998
study type: b cell assays
subject species: Trypanosoma cruzi
fullName:
C C Motrá
n
F M Cerbá
W Rivarola
D Iosa
E Vottero de Cima
method:
in vivo assay
name:
Trypanosoma cruzi: immune response and functional heart damage induced in mice by the main linear B-cell epitope of parasite ribosomal P proteins.
description:
Mice immunized with R13 EEEDDDMGFGLFD were challenged with T cruzi, and the level of parasitemia detected at 15, 18, and 20 days after infection was lower than in control mice. Immunized mice also had definite ECG abnormalities such as diminished heart frequency and intraventricular conduction disturbances.

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