Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence.

Title:

Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence.

identifier:	1465922
description:	epitope description:VPNLRGDLQVLAQKVARTLP antigen name:Polyprotein host organism:Cavia porcellus antibody name:Guinea pig sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	7045684

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1) (O1 Kaufbeuren)

fullName:	J L Bittle R A Houghten H Alexander T M Shinnick J G Sutcliffe R A Lerner D J Rowlands F Brown

method:	biological activity

name:	Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence.
description:	Swiss-Prot positions are based on the full-length polyprotein, whereas author-assigned positions correspond to the VP1 portion of the polyprotein. All animals in both groups receiving 200 μg of this conjugated peptide had significant neutralization titers using either aluminum hydroxide gel or Freund's adjuvant. In groups receiving 20 μg of conjugated peptide, titers ranged from baseline to significant.

name:	iedb
homePage:	http://www.iedb.org

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