Induction of an antigen-specific immune response and partial protection of cattle against challenge infection with foot-and-mouth disease virus (FMDV) after lipopeptide vaccination with FMDV-specific B-cell epitopes.

Title:

Dataset

identifier:	1466088
description:	epitope description:GPYAGPMERQKPLK antigen name:Polyprotein host organism:Bos taurus antibody name:Bovine sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	14645912

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006360
landingPage:	http://www.iedb.org/assay/1466088

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1) (O1 Kaufbeuren)

Person

fullName:	Bettina-Judith Hö hlich Karl-Heinz Wiesmü ller Bernd Haas Wilhelm Gerner Roberto Correa Hans-Robert Hehnen Tobias Schlapp Eberhard Pfaff Armin Saalmü

Data Type

method:	ELISA

Study

name:	Induction of an antigen-specific immune response and partial protection of cattle against challenge infection with foot-and-mouth disease virus (FMDV) after lipopeptide vaccination with FMDV-specific B-cell epitopes.
description:	Linear B cell epitopes were identified by screening 442 overlapping tetra- and pentadeca-peptides spanning the entire ORF of FMDV O1K using sera from infected cattle. Two of the 2 animals with FMDV Asia 1 Shamir responded to the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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