Kinetic analysis of synthetic analogues of linear-epitope peptides of glycoprotein D of herpes simplex virus type 1 by surface plasmon resonance.

Title:

Kinetic analysis of synthetic analogues of linear-epitope peptides of glycoprotein D of herpes simplex virus type 1 by surface plasmon resonance.

identifier:	1378750
description:	epitope description:LKMADPNRFRG antigen name:Envelope glycoprotein D host organism:Mus musculus BALB/c antibody name:A16
aggregation:	instance of dataset
availability:	available
primaryPublications:	8797855

study type:	b cell assays
subject species:	Human alphaherpesvirus 1

fullName:	E Lasonder G A Schellekens D G Koedijk R A Damhof S Welling-Wester M Feijlbrief A J Scheffer G W Welling

method:	surface plasmon resonance (SPR)

name:	Kinetic analysis of synthetic analogues of linear-epitope peptides of glycoprotein D of herpes simplex virus type 1 by surface plasmon resonance.
description:	The epitope-specific mAb A16 bound to a synthetic analog (LKXDPNRFRG, where X=norleucine) of the epitope by surface plasmon resonance. Further studies using truncated and substituted peptides demonstrate that the minimal sequence bound by the antibody is the sequence gD 11-17 (MADPNRF) and that position D13 is an essential residue while R16 and F17 are involved in structure stabilization.

name:	iedb
homePage:	http://www.iedb.org

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