Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.
identifier: 1378803
description:
epitope description:AINPESDQPDLSNF
antigen name:Acetylcholine receptor subunit alpha (UniProt:P02708)
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 2551924
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004146
landingPage: http://www.iedb.org/assay/1378803
type:
Literature
publicationVenue:
J Clin Invest
dates:
1989
study type: b cell assays
subject species: Homo sapiens
fullName:
P L Schwimmbeck
T Dyrberg
D B Drachman
M B Oldstone
method:
immuno staining
name:
Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.
description:
Affinity purified epitope-specific antibodies from patients cross-reacted with HSV infected cells by immunofluorescent staining. The antibodies bound native AChR and blocked interaction between AChR and alpha-bungarotoxin.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston