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Title: Antibodies to an Epstein-Barr virus nuclear antigen synthetic peptide in infectious mononucleosis. Report of two cases.
identifier: 1379003
description:
epitope description:AGAGGGAGGAGAGGGAGGAG
antigen name:Epstein-Barr nuclear antigen 1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 2552793
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004451
landingPage: http://www.iedb.org/assay/1379003
type:
Literature
publicationVenue:
Am J Clin Pathol
dates:
1989
study type: b cell assays
subject species: Human gammaherpesvirus 4
fullName:
R S Smith
G Rhodes
J E Geltosky
C A Horwitz
method:
ELISA
name:
Antibodies to an Epstein-Barr virus nuclear antigen synthetic peptide in infectious mononucleosis. Report of two cases.
description:
This peptide was synthesized and tested with a C-terminal cystein residue.
Using sequential sera from two donors with infectious mononucleosis, the antibody response was monitored. A specific IgM response was detected to the epitope during the acute phase of the illness, while in the convalescent phase the response was IgG-dominated, with a decline in IgM levels. This response was observed in both heterophil-positive and heterophil-negative EBV infectious mononucleosis.

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