Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1004726 |
| landingPage: |
http://www.iedb.org/assay/1379204 |
| type: |
Literature
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| publicationVenue: |
Scand J Immunol
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| dates: |
1994
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| study type: | b cell assays |
| subject species: | Human alphaherpesvirus 1 |
| fullName: |
A Hilbert
F Hudecz
G Mezô
I Mucsi
J Kajtá
r
I Kurucz
J Gergely
E Rajnavö
lgyi
|
| method: |
in vivo assay
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| name: |
The influence of branched polypeptide carriers on the immunogenicity of predicted epitopes of HSV-1 glycoprotein D.
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| description: |
The positions assigned by the authors are in the mature protein.
Fifty percent of BALB/c and 65% of CBA mice immunized with the epitope conjugated to a branched carrier (AK) were protected against lethal challenge with HSV-1. BALB/c mice immunized with the LAK-epitope conjugate were not protected. Sera from surviving mice taken 3 weeks after viral challenge neutralized HSV-1 in vitro.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
