Recognition of synthetic 104-mer and 102-mer peptides corresponding to N- and C-terminal nonrepeat regions of the Plasmodium falciparum circumsporozoite protein by sera from human donors.

Title:

Recognition of synthetic 104-mer and 102-mer peptides corresponding to N- and C-terminal nonrepeat regions of the Plasmodium falciparum circumsporozoite protein by sera from human donors.

Dataset

identifier:	1379538
description:	epitope description:NAVKNNNNEEPSDKHIEQYLKKIKNSISTEW antigen name:Circumsporozoite (CS) protein host organism:Homo sapiens antibody name:Human sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	8916800

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004821
landingPage:	http://www.iedb.org/assay/1379538

Publication

type:	Literature
publicationVenue:	Am J Trop Med Hyg
dates:	1996

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum 7G8

Person

fullName:	J A Lopez M A Roggero O Duombo J M Gonzalez R O Koita M Arevalo-Herrera S Herrera G Corradin

Data Type

method:	ELISA

Study

name:	Recognition of synthetic 104-mer and 102-mer peptides corresponding to N- and C-terminal nonrepeat regions of the Plasmodium falciparum circumsporozoite protein by sera from human donors.
description:	Sera from responding donors from Zacarias (low incidence) and Safo (high incidence) recognized this deduced epitopic region within the CS polypeptide. This region is known to contain the well-established Th2 epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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