Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1004804 |
| landingPage: |
http://www.iedb.org/assay/1379700 |
| type: |
Literature
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| publicationVenue: |
Protein Expr Purif
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| dates: |
2006
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| study type: | b cell assays |
| subject species: | Hepatitis C virus subtype 3g |
| fullName: |
Chugh A Dipti
S K Jain
Khanna Navin
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| method: |
ELISA
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| name: |
A novel recombinant multiepitope protein as a hepatitis C diagnostic intermediate of high sensitivity and specificity.
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| description: |
This peptide is stated to correspond to an Indian isolate of HCV genotype 3g.
Serum (at 1:100 dilution) raised against this peptide recognizes a recombinant multiepitope synthetic protein that contains this and other 5 antigenic regions from HCV proteins. This indicates that this epitope is accessible to its cognate antibodies in the context of the multiepitope protein. That protein was assessed next for sensitivity and specificity in a diagnostic anti-HCV EIA, giving a 100% specificity and 99.8% sensitivity. The carrier was composed of r-HCV-F-MEP.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
