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identifier: 1380792
description:
epitope description:SLFTPGP
antigen name:Genome polyprotein
host organism:Homo sapiens
antibody name:human sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 8890039
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004807
landingPage: http://www.iedb.org/assay/1380792
type:
Literature
publicationVenue:
J Med Virol
dates:
1996
study type: b cell assays
subject species: Hepatitis C virus
fullName:
Y Nakamoto
S Kaneko
H Ohno
M Honda
M Unoura
S Murakami
K Kobayashi
method:
ELISA
name:
B-cell epitopes in hypervariable region 1 of hepatitis C virus obtained from patients with chronic persistent hepatitis.
description:
The peptide is derived from a consensus sequence of residues 384-414 from hypervariable domain 1 (HVR1) within the N-terminus of the HCV E2 protein.
An increase in serum titer to the epitope was observed after IFN-alpha2b treatment in 2 of 3 patients with chronic hepatitis C. Before treatment, only one patient reacted with the epitope from the hypervariable domain 1 (HVR1) within the N-terminus of the E2 protein.