Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles.

Title:

Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles.

Dataset

identifier:	1383504
description:	epitope description:RHKQKIVAPVKQTL antigen name:Polyprotein host organism:Bos taurus antibody name:Bovine sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	1718244

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004041
landingPage:	http://www.iedb.org/assay/1383504

Publication

type:	Literature
publicationVenue:	Arch Virol
dates:	1991

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1)

Person

fullName:	S Kit M Kit R D DiMarchi S P Little C Gale

Data Type

method:	in vivo assay

Study

name:	Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles.
description:	Calves vaccinated with the recombinant IBRV-FMDV (dimer) virus generated antibodies to the VP1 epitopes. These animals were then challenged with virulent IBRV (Cooper) at 35 days post-immunization. Vaccinated calves were protected from clinical signs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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