Characterization and sequence analyses of antibody-selected antigenic variants of herpes simplex virus show a conformationally complex epitope on glycoprotein H.

Title:

Characterization and sequence analyses of antibody-selected antigenic variants of herpes simplex virus show a conformationally complex epitope on glycoprotein H.

Dataset

identifier:	1384067
description:	epitope description:D168 antigen name:Envelope glycoprotein H host organism:Mus musculus antibody name:LP11
aggregation:	instance of dataset
availability:	available
primaryPublications:	1707982

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004050
landingPage:	http://www.iedb.org/assay/1384067

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1991

Dimension

study type:	b cell assays
subject species:	Human herpesvirus 1 103/65

Person

fullName:	U A Gompels A L Carss C Saxby D C Hancock A Forrester A C Minson

Data Type

method:	biological activity

Study

name:	Characterization and sequence analyses of antibody-selected antigenic variants of herpes simplex virus show a conformationally complex epitope on glycoprotein H.
description:	The authors derived this interacting residue from a clinical isolate of HSV-1 designated 103/65. Sequence analysis of antibody-resistant mutant viruses was utilized to identify this conformational epitope on glycoprotein H of a clinical isolate (103/65) of HSV-1.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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