Identification of an immunodominant sequential epitope in glycoprotein G of herpes simplex virus type 2 that is useful for serotype-specific diagnosis.

Title:

Identification of an immunodominant sequential epitope in glycoprotein G of herpes simplex virus type 2 that is useful for serotype-specific diagnosis.

Dataset

identifier:	1385115
description:	epitope description:PEEFEGAGDGEPPEDDDS antigen name:Envelope glycoprotein G host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9700637

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004424
landingPage:	http://www.iedb.org/assay/1385115

Publication

type:	Literature
publicationVenue:	J Med Virol
dates:	1998

Dimension

study type:	b cell assays
subject species:	Human alphaherpesvirus 2

Person

fullName:	H S Marsden K MacAulay J Murray I W Smith

Data Type

method:	ELISA

Study

name:	Identification of an immunodominant sequential epitope in glycoprotein G of herpes simplex virus type 2 that is useful for serotype-specific diagnosis.
description:	The peptide was synthesized as a multiple antigenic peptide consisting of four copies of a the epitope attached to a branched lysine core and separated from the core by four glycine residues (PEEFEGAGDGEPPEDDDSG₄)K₃A). The epitope did not react with any sera lacking HSV-specific antibodies or with sera from HSV- 1-infected individuals, but did react with sera from HSV-2-infected individuals.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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