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identifier: 1402988
description:
epitope description:CVLESHYEC
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 15700752
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004817
landingPage: http://www.iedb.org/assay/1402988
type:
Literature
publicationVenue:
Parasitology
dates:
2005
study type: b cell assays
subject species:
fullName:
S Eda
I W Sherman
method:
phage display
name:
Selection of peptides recognized by human antibodies against the surface of Plasmodium falciparum-infected erythrocytes.
description:
This peptide is a potentially a mimotope of P.falciparum-infected erythrocytes membrane antigens, but no homology to described antigens is reported. A library of phage displayed random 7-mers was panned. Each peptide includes cysteine residues at bothe ends to constrain the conformation of the displayed peptide.
The phage clone containing this peptide was selected by panning the phage display library with antibodies from P.falciparum infected individuals affinity purified for recognition of P.falciparum FCR-3 infected erythrocytes.

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