Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1004655 |
| landingPage: |
http://www.iedb.org/assay/1403752 |
| type: |
Literature
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| publicationVenue: |
Virology
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| dates: |
2003
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| study type: | b cell assays |
| subject species: | Human herpesvirus 5 strain AD169 |
| fullName: |
Johan Lantto
Jean M Fletcher
Mats Ohlin
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| method: |
immuno staining
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| name: |
Binding characteristics determine the neutralizing potential of antibody fragments specific for antigenic domain 2 on glycoprotein B of human cytomegalovirus.
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| description: |
The epitope specific antibody was shown to bind to HCMV strain AD169-infected cells. The ability of a clonally related repertoire of antibody fragments to neutralize the virus varied greatly depending on the fine-specificity and kinetics of the interaction with the antigen. Similar results were obtained when the half-lives of scFv and antigen were measured using BIAcore.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
