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identifier: 1404124
description:
epitope description:LKMADPNRFRG
antigen name:Envelope glycoprotein D
host organism:Mus musculus
antibody name:A16
aggregation:
instance of dataset
availability:
available
primaryPublications: 14624643
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004600
landingPage: http://www.iedb.org/assay/1404124
type:
Literature
publicationVenue:
Bioconjug Chem
dates:
2003
study type: b cell assays
subject species: Human alphaherpesvirus 1
fullName:
bor Mezö
Eliandre de Oliveira
Dimitrios Krikorian
Matty Feijlbrief
Annamá
ria Jakab
Vassilios Tsikaris
Constantinos Sakarellos
Sytske Welling-Wester
David Andreu
Ferenc Hudecz
method:
ELISA
name:
Synthesis and comparison of antibody recognition of conjugates containing herpes simplex virus type 1 glycoprotein D epitope VII.
description:
Welling-Wester et al. (1994). Arch Virol. 138: 331-340. [PMID: 7527999]Lasonder et al. (1996). Eur J Biochem. 240: 209-214. [PMID: 8797855 ]
By direct binding and competition ELISAs, the epitope-specific mAb A16 bound to an analog of the epitope, the peptide LK(Nle)ADPNRFRGKDL (methionine is replaced by norleucine), either as a peptide or linked to various types of carrier molecules (tetratuftsin analog sequential oligopeptide carrier, branched chain polypeptide, poly-Lys, MAP and KLH). The epitope analog is recognized more efficiently with the carrier molecules than as a free peptide.

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