Monoclonal antibodies to denatured ragweed pollen allergen Amb a I: characterization, specificity for the denatured allergen, and utilization for the isolation of immunogenic peptides of Amb a I.

Title:

Monoclonal antibodies to denatured ragweed pollen allergen Amb a I: characterization, specificity for the denatured allergen, and utilization for the isolation of immunogenic peptides of Amb a I.

Dataset

identifier:	1409414
description:	epitope description:GMLATVAFNTFTDNVDQR antigen name:Amb a 1 host organism:Mus musculus BALB/c antibody name:JB1C6-5, JB3D3-3, JB4F3-5, JB5F2-2
aggregation:	instance of dataset
availability:	available
primaryPublications:	2456454

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005673
landingPage:	http://www.iedb.org/assay/1409414

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	1988

Dimension

study type:	b cell assays
subject species:	Ambrosia artemisiifolia

Person

fullName:	J J Smith J R Olson D G Klapper

Data Type

method:	antigen inhibition

Study

name:	Monoclonal antibodies to denatured ragweed pollen allergen Amb a I: characterization, specificity for the denatured allergen, and utilization for the isolation of immunogenic peptides of Amb a I.
description:	The epitope inhibited the binding in an ELISA of mAbs JB1C6-5, JB3D3-3, JB4F3-5, and JB5F2-2 to Amb a 1 by 78%, 60%, 47%, or 94%, respectively.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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