A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis.

Title:

A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis.

Dataset

identifier:	1409758
description:	epitope description:3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid antigen name:lipopolysaccharide host organism:Mus musculus BALB/c antibody name:A20
aggregation:	instance of dataset
availability:	available
primaryPublications:	16282606

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1001106
landingPage:	http://www.iedb.org/assay/1409758

Publication

type:	Literature
publicationVenue:	Glycobiology
dates:	2006

Dimension

study type:	b cell assays
subject species:	Chlamydiae

Person

fullName:	Sven Mü ller-Loennies Sabine Gronow Lore Brade Roger MacKenzie Paul Kosma Helmut Brade

Data Type

method:	western blot

Study

name:	A monoclonal antibody against a carbohydrate epitope in lipopolysaccharide differentiates Chlamydophila psittaci from Chlamydophila pecorum, Chlamydophila pneumoniae, and Chlamydia trachomatis.
description:	This epitope is a 3-deoxy-D-manno-octulosonic acid (Kdo) saccharide of genus-specific LPS of Chlamydia. Epitope specific mAb A20 bound LPS and O-deacylated LPS from recombinant E. coli encoding Kdo transferase WaaA from Chlamydophila trachomatis, C. pneumoniae, or C. psittaci. Similar results were obtained with LPS generated by in vitro reaction.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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