Detection of human antibodies using ""convergent"" combinatorial peptide libraries or ""mixotopes"" designed from a nonvariable antigen: application to the EBV viral capsid antigen p18.

Title:

Detection of human antibodies using ""convergent"" combinatorial peptide libraries or ""mixotopes"" designed from a nonvariable antigen: application to the EBV viral capsid antigen p18.

Dataset

identifier:	1409790
description:	epitope description:AVDTGSGGGGQPHDTAPRGARKKQ antigen name:Capsid protein VP26 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	9924994

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004439
landingPage:	http://www.iedb.org/assay/1409790

Publication

type:	Literature
publicationVenue:	J Pept Res
dates:	1998

Dimension

study type:	b cell assays
subject species:	Human herpesvirus 4 strain B95-8

Person

fullName:	D C Auriault E Diesis H Gras-Masse

Data Type

method:	ELISA

Study

name:	Detection of human antibodies using ""convergent"" combinatorial peptide libraries or ""mixotopes"" designed from a nonvariable antigen: application to the EBV viral capsid antigen p18.
description:	Sera from EBV-seropositive patients reacted with the epitope by ELISA. Mixotopes (convergent combinatorial peptide libraries) representing the epitope were synthesized and were successfully used to enhance the sensitivity of immunoenzymatic EBV-serodiagnosis.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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