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identifier: 1410605
description:
epitope description:3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 2294050
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1000630
landingPage: http://www.iedb.org/assay/1410605
type:
Literature
publicationVenue:
Infect Immun
dates:
1990
study type: b cell assays
subject species: Chlamydiae
fullName:
L Brade
O Holst
P Kosma
Y X Zhang
H Paulsen
R Krausse
H Brade
method:
biological activity
name:
Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide.
description:
This epitope is disaccharide of alpha-3-deoxy-D-manno-2-octulosonic acid (KDO) derived from chlamydia LPS.
Hemolysis assay was carried out with antigen-coated sheep RBC in the presence of antibodies and complements. Sera from animals immunized with heat-killed recombinant Salmonella minnesota expressing chlamydial genus-specific LPS or the purified LPS-incorporated liposome did not recognize the epitope although bound the LPS. The carrier was composed of GlcNhm2.

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