Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1005860 |
| landingPage: |
http://www.iedb.org/assay/1410461 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2000
|
| study type: | b cell assays |
| subject species: | Clostridium botulinum C 92-13 |
| fullName: |
D Blö
cker
H Barth
E Maier
R Benz
J T Barbieri
K Aktories
|
| method: |
western blot
|
| name: |
The C terminus of component C2II of Clostridium botulinum C2 toxin is essential for receptor binding.
|
| description: |
The complete recombinant C2II toxin component, its active form (after tryptic activation), and fragments of it that include domain 4 where this epitope is located, can be detected by anti-peptide antisera. Nevertheless, the oligomeric form of active C2II is not detected suggesting that in the oligomer this epitope is hidden or in a conformation not accessible to the specific antibodies.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
