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identifier: 1415599
description:
epitope description:PAADRAAAPDAVAA
antigen name:Genome polyprotein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 10092013
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1004910
landingPage: http://www.iedb.org/assay/1415599
type:
Literature
publicationVenue:
J Gen Virol
dates:
1999
study type: b cell assays
subject species: Hepatitis C virus genotype 3
fullName:
M Rodrí
guez-Ló
pez
J I Riezu-Boj
M Ruiz
C Berasain
M P Civeira
J Prieto
F Borrá
s-Cuesta
method:
ELISA
name:
Immunogenicity of variable regions of hepatitis C virus proteins: selection and modification of peptide epitopes to assess hepatitis C virus genotypes by ELISA.
description:
This peptide is an analog of peptide 2296-2309 (PLLDRWKAPDYVPP) from NS5a protein of HCV3, where residues 2,3,6,7,11,13 and 14 have been replaced by alanine. The author's provided positions may not match the Swiss-prot/Genebank positions as the author indicates the position relative to a consensus HCV genotype.
Additional alanine residue(s) were added to the synthesized peptide at the C- terminal end, and in some cases at the N-terminal end as well, for ease of synthesis and to improve binding to the solid phase of short peptides.

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