Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1005896 |
| landingPage: |
http://www.iedb.org/assay/1416669 |
| type: |
Literature
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| publicationVenue: |
J Virol
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| dates: |
2004
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| study type: | b cell assays |
| subject species: | Bovine herpesvirus 5 strain TX89 |
| fullName: |
A Al-Mubarak
Y Zhou
S I Chowdhury
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| method: |
western blot
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| name: |
A glycine-rich bovine herpesvirus 5 (BHV-5) gE-specific epitope within the ectodomain is important for BHV-5 neurovirulence.
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| description: |
The anti-gE5 epitope-specific antibody detected the gE5 protein band from the wild-type (BHV-5) virus lysate, but not from the gE5 epitope-deleted BHV-5 lysates. In separate pulse-chase experiments visualized through immunoprecipitation analysis, these antibodies also bound the epitope. The gE5 epitope-deleted virus has reduced neural spread and neurovirulence.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
