Identification of IgE- and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy.

Title:

Identification of IgE- and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy.

identifier:	1420164
description:	epitope description:GYLEQLLRLKKYKVPQ antigen name:Bos d 9 host organism:Homo sapiens antibody name:patient sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	11174208

study type:	b cell assays
subject species:	Bos taurus

fullName:	P Chatchatee K M Jä rvinen L Bardina K Beyer H A Sampson

method:	ELISA

name:	Identification of IgE- and IgG-binding epitopes on alpha(s1)-casein: differences in patients with persistent and transient cow's milk allergy.
description:	The epitope sequence was deduced through study of overlapping decapeptides spanning the sequence of alpha-S1-casein. The epitope was a major IgG binding region based on cumulative densitometric ODs. The epitope was recognized by 56% of patients (> 9 years) with persistent cow's milk allergy (CMA) and by 63% of younger patients (< 3 years), who are likely to outgrow their CMA. The epitope sequence partially overlaps an IgE binding epitope (residues 83-102).

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.