Identification of type-specific domains within glycoprotein G of herpes simplex virus type 2 (HSV-2) recognized by the majority of patients infected with HSV-2, but not by those infected with HSV-1.

Title:

Identification of type-specific domains within glycoprotein G of herpes simplex virus type 2 (HSV-2) recognized by the majority of patients infected with HSV-2, but not by those infected with HSV-1.

Dataset

identifier:	1420203
description:	epitope description:PEKTPLPVSATAMAPSVDPS antigen name:Envelope glycoprotein G host organism:Mus musculus antibody name:F11
aggregation:	instance of dataset
availability:	available
primaryPublications:	10423148

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004387
landingPage:	http://www.iedb.org/assay/1420203

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	1999

Dimension

study type:	b cell assays
subject species:	Human alphaherpesvirus 2

Person

fullName:	A Grabowska C Jameson P Laing S Jeansson E Sjö gren-Jansson J Taylor A Cunningham W L Irving

Data Type

method:	western blot

Study

name:	Identification of type-specific domains within glycoprotein G of herpes simplex virus type 2 (HSV-2) recognized by the majority of patients infected with HSV-2, but not by those infected with HSV-1.
description:	A random phage peptide display library was used to identify antigenic regions using a panel of mAbs specific to the HSV-2 gG2 protein. Further localization of epitopes was accomplished using synthetic peptides derived from the mAb-selected clone sequence.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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