Immunization with a peptide derived from the G glycoprotein of bovine respiratory syncytial virus (BRSV) reduces the incidence of BRSV-associated pneumonia in the natural host.

Title:

Immunization with a peptide derived from the G glycoprotein of bovine respiratory syncytial virus (BRSV) reduces the incidence of BRSV-associated pneumonia in the natural host.

Dataset

identifier:	1460307
description:	epitope description:STCEGNLACLSLSK host organism:Mus musculus BALB/c antibody name:Mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	9302749

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006311
landingPage:	http://www.iedb.org/assay/1460307

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1997

Dimension

study type:	b cell assays
subject species:

Person

fullName:	N Bastien G L H Thomas S G Wyld C Simard M

Data Type

method:	ELISA

Study

name:	Immunization with a peptide derived from the G glycoprotein of bovine respiratory syncytial virus (BRSV) reduces the incidence of BRSV-associated pneumonia in the natural host.
description:	This protein was derived from the G protein epitope 174-187 of BRSV (strain 391-2). Here, residues 186 (C to S) and 187 (H to K) have been altered. Mice immunized with the epitope conjugated to KLH produced BRSV-specific antibodies 100-fold higher than controls. These antibodies were found to be non-neutralizing in a separate assay.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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