Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen.

Title:

Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen.

Dataset

identifier:	1434748
description:	epitope description:RGETPGQLLPEIMQ antigen name:nucleocapsid protein host organism:Capra hircus antibody name:goat serum
aggregation:	instance of dataset
availability:	available
primaryPublications:	16962260

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006060
landingPage:	http://www.iedb.org/assay/1434748

Publication

type:	Literature
publicationVenue:	Vet Microbiol
dates:	2006

Dimension

study type:	b cell assays
subject species:	Small ruminant morbillivirus

Person

fullName:	H J Dechamma V Dighe C Ashok Kumar R P Singh M Jagadish Satish Kumar

Data Type

method:	ELISA

Study

name:	Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen.
description:	Additional peptides contained within the epitope (LLPEIMQ, TPGQLLPEIMQ, ETPGQLLPEIMQ) were recognized in a multiple antigenic peptide (MAP) configuration - only the 12mer peptide (ETPGQLLPEIMQ) gave a response that rivaled that of the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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