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identifier: 1459587
description:
epitope description:NATAEGRAINRRVE
antigen name:Outer membrane porin F
host organism:Mus musculus C57BL/6
antibody name:Mouse serum
aggregation:
instance of dataset
availability:
available
primaryPublications: 15841217
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006282
landingPage: http://www.iedb.org/assay/1459587
type:
Literature
publicationVenue:
J Clin Invest
dates:
2005
study type: b cell assays
subject species: Pseudomonas aeruginosa
fullName:
Stefan Worgall
Anja Krause
Michael Rivara
Kyung-Kim Hee
Enrico V Vintayen
Neil R Hackett
Peter W Roelvink
Joseph T Bruder
Thomas J Wickham
Imre Kovesdi
Ronald G Crystal
method:
ELISA
name:
Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.
description:
In addition to C57BL/6 (H2-Ab), two other strains of mice, BALB/c (H2-Ed) and CBA (H2-Ek), were immunized and assayed. All strains produced significant amounts of anti-epitope antibodies, including IgG1, IgG2a, and IgG2b isotypes in BALB/c mice and IgG2a, IgG2b, and IgG3 isotypes in CBA mice.

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