Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding.

Title:

Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding.

Dataset

identifier:	1463707
description:	epitope description:VVIANNVDKFVSWGITDFEM antigen name:KxYKxGKxW signal domain protein host organism:Rattus norvegicus Rowett antibody name:Rat sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	17088351

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006555
landingPage:	http://www.iedb.org/assay/1463707

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	2007

Dimension

study type:	b cell assays
subject species:	Streptococcus sobrinus 6715

Person

fullName:	S Culshaw K Larosa H X Han J W Eastcott D J Smith M A Taubman

Data Type

method:	ELISA

Study

name:	Immunogenic and protective potential of mutans streptococcal glucosyltransferase peptide constructs selected by major histocompatibility complex class II allele binding.
description:	Antibodies from MAP 11-immunized rats recognized intact GTF. While GTF-specific reactivity was achieved following both salivary gland and intranasal immunization, higher titers were seen for the former modality.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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