A recombinant subunit vaccine based on the insertion of 27 amino acids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev.1 vaccination.

Title:

A recombinant subunit vaccine based on the insertion of 27 amino acids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev.1 vaccination.

Dataset

identifier:	1462969
description:	epitope description:NAGYAGGKFKHPFSSFDKEDNEQVSGS antigen name:31 kDa outer-membrane immunogenic protein host organism:Mus musculus BALB/c antibody name:Anti-rBLSOmp31 mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	17442465

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006653
landingPage:	http://www.iedb.org/assay/1462969

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	2007

Dimension

study type:	b cell assays
subject species:	Brucella melitensis

Person

fullName:	Juliana Cassataro Karina A Pasquevich Silvia M Estein Diego A Laplagne Carlos A Velikovsky Silvia de la Barrera Raú l Bowden Carlos A Fossati Guillermo H Giambartolomei Fernando A Goldbaum

Data Type

method:	ELISA

Study

name:	A recombinant subunit vaccine based on the insertion of 27 amino acids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev.1 vaccination.
description:	In antisera generated against the Omp31 peptide fused to BLS, the IgG1 response predominanted over the IgG2a response in reactivity to the Omp31 protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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