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Title: Epitope mapping and features of the epitope for monoclonal antibodies inhibiting enzymatic activity of Helicobacter pylori urease.
identifier: 220
description:
epitope description:IFGFNALVDR
antigen name:Urease subunit alpha
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 15112296
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/319
landingPage: http://www.iedb.org/assay/220
type:
Literature
publicationVenue:
Biotechnol Bioeng
dates:
2004
study type: b cell assays
subject species: Helicobacter pylori
fullName:
Ryoji Fujii
Fumiko Morihara
Takashi Oku
Emi Hifumi
Taizo Uda
method:
ELISA
name:
Epitope mapping and features of the epitope for monoclonal antibodies inhibiting enzymatic activity of Helicobacter pylori urease.
description:
This epitope is present as a part of a loop structure at a position close to the C-terminal of the a-subunit of H. pylori urease.
LP-polyclonal (affinity-purified) serum reacted with H. pylori urease by a factor of over 10-fold (the estimated affinity constant is about 10-10/M) stronger than to the antigenic Long-peptide.

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