Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 3298 |
| description: |
epitope description:P330, N331, D332, P333, T334, Y342, G344, N345, I367, I369, A370, S371, S373, N400, T401, W403
antigen name:Neuraminidase
host organism:Mus musculus BALB/c
antibody name:NC10
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
7994573 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/498 |
| landingPage: |
http://www.iedb.org/assay/3298 |
| type: |
Literature
|
| publicationVenue: |
Structure
|
| dates: |
1994
|
| study type: | b cell assays |
| subject species: | Influenza A virus (A/whale/Maine/1/84(H13N9)) |
| fullName: |
R L Malby
W R Tulip
V R Harley
J L McKimm-Breschkin
W G Laver
R G Webster
P M Colman
|
| method: |
x-ray crystallography
|
| name: |
The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody.
|
| description: |
The epitope of NC10 Fab on N9 neuraminidase was determined from the crystal structure of the complex. In the complex, the neuraminidase-Fab protomers are closely packed along the four-fold rotation axis of the crystals. The four Fab fragments bind to the upper surface (distal to to the viral membrane) of the neuraminidase tetramer.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
