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Title: Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation.
identifier: 1994
description:
epitope description:W155, S156, I157, Q158, N159, C203, Y204, D205, M206, K207, T208, T209, C210
antigen name:Integrin beta-3
host organism:Mus musculus
antibody name:10E5
aggregation:
instance of dataset
availability:
available
primaryPublications: 15277669
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/433
landingPage: http://www.iedb.org/assay/1994
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2004
study type: b cell assays
subject species: Homo sapiens
fullName:
Andrea Artoni
JiHong Li
Beau Mitchell
Jian Ruan
Junichi Takagi
Timothy A Springer
Deborah L French
Barry S Coller
method:
flow cytometry
name:
Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation.
description:
The percentage of 293T cells expressing alphaIIb binding to 10E5 as measured by flow cytometry was 42% +/- 12. The antigen in this assay was the beta3Hu epitope expressed in 293T cells.

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