High epitope density in a single protein molecule significantly enhances antigenicity as well as immunogenicity: a novel strategy for modern vaccine development and a preliminary investigation about B cell discrimination of monomeric proteins.

Title:

Dataset

identifier:	2125
description:	epitope description:SLLTEVETPIRNEWGCRCNDSSD antigen name:Matrix protein 2 host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	15627976

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/448
landingPage:	http://www.iedb.org/assay/2125

Publication

type:	Literature
publicationVenue:	Eur J Immunol
dates:	2005

Dimension

study type:	b cell assays
subject species:	Influenza A virus

Person

fullName:	Wanli Liu Ying-Hua Chen

Data Type

method:	ELISA

Study

name:	High epitope density in a single protein molecule significantly enhances antigenicity as well as immunogenicity: a novel strategy for modern vaccine development and a preliminary investigation about B cell discrimination of monomeric proteins.
description:	Antigen binding by pAb increases with the increase of the immunogen polymer length. The epitope contained an additional N-terminal K residue.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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