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Title: Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
identifier: 4737
description:
epitope description:alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp
antigen name:lipopolysaccharide
host organism:Mus musculus BALB/c
antibody name:Se155-4
aggregation:
instance of dataset
availability:
available
primaryPublications: 1713710
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/561
landingPage: http://www.iedb.org/assay/4737
type:
Literature
publicationVenue:
Science
dates:
1991
study type: b cell assays
subject species: Salmonella enterica subsp. enterica serovar Essen
fullName:
M Cygler
D R Rose
D R Bundle
method:
x-ray crystallography
name:
Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
description:
The epitope is part of the O-PS of Salmonella type B LPS repeating unit.
The crystal structure was obtained by cristallyzation with a dodesaccharide containing the epitope, but only the epitopic structure was detected in the complex, allowing for the precise determination of the trisaccharide as the epitope bound by the mAb.

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